This medication description is not meant for treatment prescription without the intervention of a specialist.

Common Uses

Mianserin is a tetracyclic antidepressant that has antihistaminic and hypnosedative, but almost no anticholinergic, effect. Mianserin is a weak inhibitor of norepinephrine reuptake and strongly stimulates the release of norepinephrine. Interactions with serotonin receptors in the central nervous system have also been found. Its effect is usually noticeable after one to three weeks.

How to Take

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. Initially, 30-40 mg in the morning; increase dosage gradually only after a trial period of several weeks if required. Maximum: 150 mg/day.

Warning and Precautions

Children, teenagers, and young adults who take Mianserin may be at increased risk for suicidal thoughts or actions. Watch all patients who take Mianserin closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.

Missed Dose

If you miss a dose of Mianserin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Overdose

Symptoms of overdose may include: coma, fainting, fast, slow, or irregular heartbeat, hair loss, hallucinations, seizures, severe or persistent dizziness, drowsiness, diarrhea, nausea, or vomiting, tremor. Seek emergency medical attention if you think you have used too much of this medicine.

Storage

Store Mianserin at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep out of the reach of children and away from pets.

Possible Side Effects

The common side effects are: anxiety, constipation, decreased sexual desire or ability, diarrhea, dizziness, drowsiness, dry mouth, increased sweating, loss of appetite, nausea, nervousness, stomach upset, tiredness, trouble sleeping, vomiting, weight loss.

More Information

The information given above is a summary. Your pharmacist can provide more information about Mianserin. Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. If using this medicine for an extended period of time, obtain refills before your supply runs out.