This medication description is not meant for treatment prescription without the intervention of a specialist.

Common Uses

Omeprazol is a proton pump inhibitor used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease and Zollinger-Ellison syndrome. Omeprazol is one of the most widely prescribed drugs internationally and is available over the counter in some countries. It may be used for short-term treatment of ulcers of the stomach or small intestines. It may be used to decrease the risk of stomach bleeding in severely ill patients. It may also be used for other conditions as determined by your doctor.

How to Take

Short-term Treatment of Active Duodenal Ulcer: The usual dose for adults is 20 milligrams once a day. Most people heal within 4 weeks, although some require an additional 4 weeks of Omeprazol therapy.

Treatment of Duodenal Ulcers Caused by H. Pylori: In combination therapy with Biaxin alone, the usual dosage is 40 milligrams of Omeprazol once daily and 500 milligrams of Biaxin 3 times a day for 14 days, followed by 20 milligrams of Omeprazol once daily for an additional 14 days.

If amoxicillin is included in the treatment, the recommended dosage is 20 milligrams of Omeprazol, 500 milligrams of Biaxin, and 1,000 milligrams of amoxicillin twice a day for 10 days, followed by 20 milligrams of Omeprazol once daily for an additional 18 days.

Gastric Ulcer: The usual dose is 40 milligrams once a day for 4 to 8 weeks.

Gastroesophageal Reflux Disease: The usual dose for people with symptoms of GERD is 20 milligrams daily for up to 4 weeks. For erosive esophagitis accompanied by GERD symptoms, the usual dose is 20 milligrams a day for 4 to 8 weeks.

The dose may be continued to maintain healing.

Pathological Hypersecretory Conditions: The usual starting dose is 60 milligrams once a day. If you take more than 80 milligrams a day, your doctor will divide the total into smaller doses. The dosing will be based on your needs.

Gastroesophageal Reflux Disease and Acid-Related Disorders: For children from 2 to 16 years old and weighing less than 44 pounds, the usual dose is 10 milligrams a day. For those weighing 44 pounds or more, the usual dose is 20 milligrams a day. For children with erosive esophagitis, your doctor will determine the correct dose based on the child's weight.

The safety and effectiveness of Omeprazol have not been studied in children under 2 years old.

Warning and Precautions

Long-term use of Omeprazol can cause severe stomach inflammation.

Omeprazol may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Omeprazol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Contact your doctor if you have any signs of a bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds; or if you experience throat pain, chest pain, severe stomach pain, or trouble swallowing.

Omeprazol has sodium in it. Include this when you count your daily intake of sodium.

Long-term use of Omeprazol with calcium or milk may cause milk-alkali syndrome. Check with your doctor before taking calcium supplements, antacids that contain calcium, or drinking milk while you are taking Omeprazol. Also long-term use of Omeprazol can cause severe stomach inflammation.

Both strengths of Omeprazol contain the same amount of sodium bicarbonate. Therefore, if your doctor has prescribed the 40 mg dose, do not take 2 of the 20 mg capsules to make a 40 mg dose.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Overdose

Overdose with Omeprazol has been rare, but any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately. Symptoms of Omeprazol overdose may include: blurred vision, confusion, drowsiness, dry mouth, flushing, headache, nausea, rapid heartbeat, sweating, vomiting.

Storage

Store Omeprazol at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Omeprazol out of the reach of children and away from pets.

Possible Side Effects

More common side effects may include: abdominal pain, diarrhea, headache, nausea, vomiting. When taken with Biaxin, side effects may also include: flu symptoms, nasal inflammation, sore throat, taste alteration, tongue discoloration.

More Information

The information given above is a summary. Your pharmacist can provide more information about Omeprazol. Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. If using this medicine for an extended period of time, obtain refills before your supply runs out.

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